Transforming classroom instruction requires sustained, collaborative, student-centered professional development. Macomb Intermediate School District employs a Professional Learning Community (PLC) model to help secondary teaching teams plan and implement inclusive instruction through the Universal Design for Learning (UDL) framework.  This conference proceeding presents lessons learned from seven years of UDL PLC implementation. It includes resources, tools and strategies to help educators move from a conceptual understanding of UDL to successful district, school and classroom implementation.